GEJALA KLINIS SEBAGAI PREDIKTOR PADA KARSINOMA SEL BASAL

Ratih Pramuningtyas, Prasetyadi Mawardi

DOI: https://doi.org/10.23917/biomedika.v4i1.261

Abstract

Basal Cell Carcinoma (BCC) incidence is 75% of all skin cancers. BCC rarely causing mortality, but morbidity is high. Clinical diagnostic is the early detection of BCC suspicion, therefore, we required specific criteria that help to establish the clinical diagnosis. The objective of this study was to know the clinical sign as a predictor of basal cell carcinoma. Ten patients with skin tumors who came to dermatovenereological department of Dr. Moewardi hospital were included in this study. Clinical diagnosis using clinical criteria from keratinocyte carcinoma in A Cancer Journal For Clinicians in 2011 (Teleangiectasion, raise border, erythematous with bleeding, pigmentation, translucent appearance, and scarlike appearance) was used as reference of clinical diagnostic criteria. Histopathological examination was performed as a gold standard. All 10 subjects had histopathological finding consistent to BCC. The clinical examination like pigmentation were found in all subjects while teleangiectasia, raise border, erythema with bleeding were found on 9 subject. Translucent appearance was found on 6 subjects. While scarlike appearance was absent in all subjects. The criteria from keratinocyte carcinoma in A Cancer Journal For Clinicians in 2011 can be used to diagnosed BCC clinically

Keywords : Basal cell carcinoma, Clinical Diagnostic Criteria

Full Text:

PDF

References

Carucci JA, Leffell DJ. Basal cell carcinoma, Dalam : Freedberg IM, Elsesn AZ, Wolff K, Austen KF, Goldsmith LA, Katz S, Fitzpatrick-s Dermatology In General Medicine, 7th ed, New York, McGrawHill. 2008;2029-35

Bakis S, Irwig L, Wood G, Wong D. Exfoliative cytology as a diagnostic test for basal cell carcinoma: a meta-analysis, British Journal of Dermatology, 2004, 150 : 829-36.

Tilli CMLJ, Steensel MAM, Krekels GAM. Molecular aetiology and pathogenesis of basal cell carcinoma, British Journal of Dermatology, 2005, 152 : 1108-24

Christenson LJ, Borrowman TA, Vachen CM, Tollefson MM, Otley CC, Weaver AL, Roenigk RK, Incidence of basal aell and squamous cell carsinomas in a population younger than 40 years, JAMA, 2005, 294 : 681-90

Solano JG, Rojo BG, sanchez C, Romero MS, Guilermo MP, Basal cell carcinoma : cytologic and immunocytochemical findings in fine-needle aspirates, Diagnostic Cytopathology, Vol 18 : 403-8

Altamura D, Menzies SW, Argenziano G, Zalaudek I, Soyer HP, Sera F, Avramidis M, Deambrosis K, Fargnoli MC, Peris K. Dermatoscopy of basal cell carcinoma : Morphologic variability of global and local features and accuracy of diagnosis, Journal American Academy of Dermatology, 2010, 62 : 67 - 75

Kuzmina N, Talme T, Lapins J, Emtestam L, Non-invasive preoperative assessment of basal Cell carcinoma of nodular and superficial types. Skin Research and Technology, 2005, 11 : 196 - 200

Robinson JK, Fisher SG, Turrisi RJ, Predictors of skin self-examination performance. Cancer, 2002, 95 : 135 - 146

Stoecker WV, Gupta K, Shrestha B, Wronkiewieckz, Chowdhury R, stanley RJ, Jin Xu, Moss RH, Celebi ME, Rabinovitz HS, Oliviero M, Malters, JM, Kolm I, Detection of Basal Cell Carsinoma Using Color and Histogram Measure of Semitranslucent Areas, Skin Research and Technology, 2009, 15 : 283 -87

Albert MR. and Weinstock MA, Keratinocyte Carcinoma, CA a Cancer Journal for Clinician, 2011, 53 : 292-302

Mackie RM, Quinn AG, Basal Cell Carcinoma, Dalam : Burns T, Breathnach S, Christopher G, Rook-s Text Book Of Dermatology, 7th, Blackwell Publishing, 2004, 36.19

Arnold HL, et al, Andrews disease of The Skin, 9th ed, WB Sauders co, 2000, 820 - 829 Habib TB, Clinical dermatology, 3rd ed, Mosty Missaouri, 1996, 649 - 59

Jayanta K, Widjaya HR, et al. Penanganan karsinoma sel basal dalam : Perkembangan onkologi dan bedah kulit di Indonesia. Kumpulan Makalah Lengkap PIT V Perdoski. Semarang. 2000

Mogensen M, Gregor BE, Jemec. Diagnosis of Nonmelanoma Skin Cancer/Keratinocyte Carcinoma: A Review of Diagnostic Accuracy of Nonmelanoma Skin Cancer Diagnostic Tests and Technologies. Dermatology Surgery. 2007 ; 33:1158-74

Goldberg LH, Friedman RH, Silapunt S, Pigmented speckling as a Sign of Basal Cell Carcinoma, Dermatology Surgery, 2004, 30 : 1553-55

Lever WF. Histopathology of the skin. 6rd ed. JB Lippincot Company. 1983 : 362-574

Article Metrics

Abstract view(s): 301 time(s)
PDF: 1581 time(s)

Refbacks

  • There are currently no refbacks.