PROFIL KOAGULASI PASIEN PENDERITA DIABETES MELLITUS DI RS X, KEBUMEN, JAWA TENGAH

Ester Tri Rahayu, Adika Zhulhi Arjana, Juwariyah Juwariyah, Utami Mulyaningrum, Rozan Muhammad Irfan

DOI: https://doi.org/10.23917/biomedika.v9i1.4345

Abstract

Ulkus diabetes mellitus (DM) adalah komplikasi dari diabetes mellitus yang menimbulkan dampak sosioekonomi yang besar. Morbiditas yang ditimbulkan cukup besar dan secara epidemiologi penderita DM memiliki resiko 25 % untuk terjadinya ulkus DM. Secara patofisiologinya, ulkus DM terjadi atas 3 kondisi yaitu neuropathy, gangguan vaskular, dan infeksi. Gangguan vaskular yang terjadi dimungkinkan disebabkan karena adanya gangguan dalam proses koagulasi. Penelitian ini bertujuan untuk mengetahui kondisi koagulasi pasien DM penderita ulkus DM. Penelitian ini menggunakan data sekunder rekam medis. Subyek yang masuk dalam penelitian ini adalah penderita dewasa ulkus DM. Data rekam medis subyek mengenai kondisi diabetes dan ulkus DM diambil peneliti dan dianalisis secara deskriptif. Hasil penelitian menunjukkan adanya perbedaan yang bermakna pada waktu pembekuan dan kadar SGOT pada berbagai derajat ulkus diabetikum. Akan tetapi perbedaan tidak dijumpai pada waktu perdarahan dan kadar SGPT.

 

Kata Kunci: Ulkus, koagulasi, diabetes mellitus

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