Evaluasi Penggunaan Antibiotik pada Pasien Infeksi Saluran Kemih di Instalasi Rawat Inap RSUP X di Klaten Tahun 2017

Nawang Nawakasari(1*), Ambar Yunita Nugraheni(2)

(1) Universitas Muhammadiyah Surakarta
(2) Universitas Muhammadiyah Surakarta
(*) Corresponding Author

Abstract

Urinary tract infections are infections are characterized by the presence of bacteria that grow and multiply in the urinary tract in excess of the normal amount. Based on the Indonesian Health Profile, urinary tract infections (UTI) are the 10 most common causes of death. Improper use of antibiotics can cause no therapeutic effect and resistance. This study aims to evaluate the accuracy of antibiotic use in patients with urinary tract infections in central hospital Klaten in 2017 covers the right indication, right patient, right medication, and right dosage. Research with non-experimental methods of data retrieval retrospectively and analyzed descriptively. The inclusion criteria in this study were adult patients 18-64 years old, inpatients suffering from urinary tract infections including cystitis and pyelonephritis, receiving antibiotics and complete medical record data. The results showed that patients with urinary tract infections in RSUP in Klaten 2017 had 72 patients with 76 antibiotic prescriptions. Based on the number of patients, the evaluation results showed the right indication is 100% and the right patients is 100%, while the exact evaluation results of the right drug is 96.05% and the right doses is 27,63%.

Keywords

antibiotics; urinary tract infections; evaluation; accuracy

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References

American Diabetes Association (ADA), 2013, Diabetes Care, Volume 36 1: S67 http://care.diabetesjournals.org/content/36/Supplement_1/S11.full.pdf.

Al-Badr A., dan Al-Shaikh G., 2013, Recurrent Urinary Tract Infections Management in Women, Indian Medical Journal, 13 August, 359–367.

Badan Pengawas Obat dan Makanan Republik Indonesia (BPOM RI), 2008, Informasi Obat Nasional Indonesia (IONI). BPOM RI, Jakarta.

BNF, 2016, British National Formulary 71th Edition, 71st ed., BMJ Group, London United Kingdom

Chair M. G., Bartoletti R., Bjerklund J. T. E., Cai T., Çek M., Köves B., 2015, EAU guidelines for the management of urinary and male genital tract infections, Urinary Tract Infection (UTI) Working Group of the Health Care Office (HCO) of the European Association of Urology (EAU), European Urology, 40(5), 576–588.

Coyle, E. A and Prince R.A., 2017, Urinary Tract Infection and Prostatitis, in Dipiro, J. T., Robert, L. T., Gary, C. Y., Gary, R. M., Barbara, G. W., and Michael, P., (Eds) Pharmacotherapy : A Pathophysiologic Approach, Tenth Edition, The McGraw-Hill Companies Inc, 7 th., USA.

Darnindro N. and Syam A.F., 2013, Current Diagnosis and Management of Helicobacter pylori, Faculty of Medicine University of Indonesia Journal, 14 (3), 165–173.

Depkes RI, 2011, Pedoman Umum Penggunaan Antibotik, Departemen Kesehatan RI, Jakarta.

Depkes RI, 2016, Peraturan Menteri Kesehatan No. 72 Tentang Standar Pelayanan Kefarmasian di Rumah Sakit, Departemen Kesehatan RI, Jakarta.

DIH, 2007, Drug Information Handbook 17th edition, America Pharmacist Association, New York.

Durham S.H., Aq-id B., Wingler M.J. and Eiland L.S., 2017, Appropriate Use of Ceftriaxone in the Emergency Department of a Veteran ’ s Health Care System, Journal of Pharmacy Technology, 33(6), 215 –218.

Flores M., Walker J. N., Caparon, M., dan Hultgren S. J., 2016, Urinary Tract Infections: Epidemiology, Mechanisms of Infection and Treatment Options, Department of Molecular Microbiology and Center for Women’s Infectious Disease Research, Nat Rev Microbiol, University School of Medicine ,Washington.

Ghinorawa T., 2015, Penatalaksanaan Infeksi Saluran Kemih dan Genitalia Pria 2015 2nd ed., Ikatan Ahli Urologi Indonesia, Surabaya.

Grabe M., Bartoletti R., Johansen T.E.B., Cai T., Cek M., Koves B., et al., 2015, Guidelines on Urological Infections, European Association of Urology, March 2015

Hauser, R. A., (2013) Antibiotics basics for clinicians the ABCs of choosing the right antibacterial agent. Second Edi, Chicago: Depastement of Microbiologgy/Immunology and Medicine Northwestern University, Chicago, Illinois.

Jhang J. F., dan Kuo H. C., 2017, Recent Advance in Recurrent Urinary Tract Infection from Pathogenesis and biomarkers to Prevention, Tzu Chi Medical Journal, 29(2), 65–71.

Kementerian Kesehatan RI, 2011, Tatalaksana Klinis Infeksi HIV dan Terapi Antiretroviral Pada Orang Dewasa, II., Kementerian Kesehatan RI, Jakarta.

National Kidney Foundation, 2010, Urinary Tract Infections, National Kidney Foundation Organization, New York. Http://www.kidney.org

O’neil C.K., 2016, Pain Management, Dalam DiPiro, J. T. et al., eds. Pharmacotherapy Principal and Practice, McGraw-Hill Education, New York, pp. 521–531.

PPK, Panduan Praktik Klinis RSUP X Klaten, 2017, Jawa Tengah

Purnomo, B., 2011, Dasar-Dasar Urologi, Ed 3, Sagung Seto, Jakarta

Raini M., 2016, Antibiotik Golongan Fluorokuinolon : Manfaat dan Kerugian, Pusat Penelitian dan Pengembangan Biomedis dan Teknologi Dasar, Kesehatan Badan Litbangkes, Jakarta. 26 No. 15, 1169–1174.

Ramlakhan S., Singh V., Stone J. and Ramtahal A., 2014, Clinical Medicine Insights : Pediatrics Clinical Options for the Treatment of Urinary Tract Infections in Children, Clinical Medicine Pediatric, 31–37.

RISKESDAS, 2013, Riset Kesehatan Dasar, Badan Penelitian dan Pengembangan Kesehatan Kementerian RI. (Diakses pada 14 Januari 2019).

Rose W.E., 2016, Urinary Tract Infection, Dalam DiPiro, J. T. et al., eds. Pharmacotherapy Principal and Practice, McGraw-Hill Education, New York, pp. 521–531.

Rowe T.A. and Manisha J., 2014, Urinary tract infection in older adults, National Institutes of Health, 9 (5), 1–15

Smeltzer S. C., dan Bare B. G., 2008, Textbook of Medical-Surgical Nursing, 8th edition, Philadelphia: Lippincott Williams & Wilkins.

Sutarman R. H., 2016, Evaluasi Penggunaan Antibiotik pada Pasien Infeksi Saluran Kemih Rawat Inap di RS X Kabupaten Sukoharjo Tahun 2004, Skripsi, Fakultas Farmasi, Universitas Muhammadiyah Surakarta, Surakarta.

DOI: 10.23917/pharmacon.v16i1.8113

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