Pengaruh Pasta Tomat Terhadap Kolesterol Darah Mencit

Febriani Sarwendah Asri Nugraheni(1*), Jailani Jailani(2), Sri Purwati(3)

(1) Pascasarjana Universitas Negeri Malang
(2) Prodi Pendidikan Biologi Universitas Mulawarman
(3) Prodi Pendidikan Biologi Universitas Mulawarman
(*) Corresponding Author

Abstract

This study aims to determine the effect of tomato paste on blood cholesterol in mice. It was an experimental study using a complete randomized study design consisting of four treatments P0, P1, P2, and P3 by giving tomato paste solution in a concentration of 0%, 20%, 40% and 80% and 6 replications. Data were analyzed using Anova one path and continued with BNT with a confidence level of 95%. The results showed that the tomato paste solution affected the blood cholesterol of mice due to Fhit (3.27)> F tab (3.10) and the treatment that gave the greatest effect was on giving the concentration of tomato paste solution by 80%.

Keywords

tomato pasta, mice, blood, cholesterol

Full Text:

PDF

References

Agarwal, S & Rao, AV. 2000. Tomato lycopene and its role in human health and chronic diseases, CMAJ, 163(6): 739-744.

Alda, L,M. Gogoasa, I. Despina-M, B. Gergen, I. Alda, S. Calemia, M. & Nita, L. 2009. Lycopene content of tomatoes and tomato products, Journal of Agroalimentary Processes and Technologies, 15(4): 540-542.

Bantas, K. Farida, MTA. Dinie, Z. 2012. Risiko Hiperkolesterolemia pada Pekerja di Kawasan Industri. Jurnal Kesehatan Masyarakat Nasional, 6(5): 219-224

Basu, A & Imran, V. 2007. Tomatoes Versus Lycopene in Oxidative Stress and Carcinogenesis, Eur J Clin Nutr, 61(3): 295-303.

Betteng, R. Damayanti, P & Nelly, M. 2014. Analisis Faktor Resiko Penyebab Terjadinya Diabetes Melitus Tipe 2 Pada Wanita Usia Produktif Di puskesmas Wawonasa. Jurnal e-Biomedik (eBM), 2(2): 404-412.

Bohm F. Trinkler JH. Truscott TG. Carotenoids protect against cell membrane damage by the nitrogen dioxide radical. Nat Med. 1995: 1:98–99.

Davies. 2000. Tomatoes and Health. Journal of Social Health, 120(2): 81-85.

Di Mascio P. Kaiser S. Sies H. Lycopene As The Most Efficient Biological Carotenoid Singlet Oxygen Quencher, Arch Biochem Biophys, 274:532 – 538.

Inzucchi, S. Porte, D. Sherwin, R. & Baron, A. 2005. The Diabetes Mellitus Manual : A Primary Care Companion. Edisi 1. New York: Mc Graw-Hill Companies.

Jelantik, I.G.M.G. 2014. Hubungan Faktor Risiko Umur, Jenis Kelamin, Kegemukan Dan Hipertensi Dengan Kejadian Diabetes Mellitus Tipe Ii Di Wilayah Kerja Puskesmas Mataram. Media Bina Ilmiah, 8(1): 39-44.

Jenkins, J.A & G. Mackinney. 1955. Carotenoid of the Apricot Tomato and Its Hybrids with Yellow and Tangerine, Online (http://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC1209752&blobtype=pdf), diakses 25 Oktober 2016.

Kelkel, M. Marc, S. Mario, D. & Marc, D. 2011. Antioxidant and anti-proliferative properties of lycopene, Free Radical Research, 45(8): 925-940.

Kemenkes RI. 2012. Buletin Jendela Data dan Informasi Kesehatan Penyakit Tidak Menular, Jakarta; Kemenkes RI

LIPI. 2009. Kolesterol Tinggi. Balai Informasi Teknologi LIPI, Jakarta; LIPI

Miller NJ. Sampson J. Candeias LP. Bramley PM. Rice-Evans CA. Antioxidant activities of carotenes and xanthophylls. FEBS Lett 1996; 384:240 – 242.

Nasir, M, U. Sarfaz, H. & Saqib, J. 2015. Tomato processing, lycopene and health benefits: A review, 3(1): 1-5

Shi, J. and M. LeMaguer. 2000. Lycopene in Tomatoes: Chemical and Physical Properties Affected by Food Processing. Critical Review of Food Science and Nutrition, 40(1) : 1-42.

Stancu, C. & Anca, S. 2001. Statins: Mechanism of Action and Effects, Journal of Cellular and Molecular Medicine, 5(4): 378-387

Sullivan, S, O. 2007. Statins: A review of benefits and risks. TSMJ, 8: 52- 56.

Thompson, K. A., M. R. Marshall, C. A. Sims, C. I.Wei, S. A. Sargent, J. W. Scott. 2000. Cultivar,Maturity, and Heat Treatment on Lycopene Content in Tomatoes. Journal of Food Science, 65(5): 791-795.

Williams, H. 2005. Dislipidemia-Terapi Obat, Hosppharm, Online (https://lyrawati.files.wordpress.com/2008/07/dislipidemia_obat_hosppharm1.pdf), diakses pada 25 Oktober 2016

DOI: 10.23917/bioeksperimen.v5i2.9244

Article Metrics

Abstract view(s): 613 time(s)
PDF: 659 time(s)

Refbacks

  • There are currently no refbacks.