GAMBARAN SKRINING METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS (MRSA) PADA PASIEN ORTOPEDI DI RS X RIAU

Dewi Anggraini(1*), Muhammad Ihsan(2), Maya Savira(3), Fauzia Andrini Djojosugito(4), Farah Mardhiyah(5)

(1) Program Pendidikan Doktor, Fakultas Kedokteran, Universitas Airlangga Departemen Mikrobiologi, Fakultas Kedokteran, Universitas Riau
(2) Departemen Bedah, Divisi Ortopedi, Fakultas Kedokteran, Universitas Riau
(3) Departemen Mikrobiologi, Fakultas Kedokteran, Universitas Riau
(4) Departemen Mikrobiologi, Fakultas Kedokteran, Universitas Riau
(5) Program Studi Pendidikan Dokter, Fakultas Kedokteran, Universitas Riau
(*) Corresponding Author

Abstract

ABSTRAK

Methicillin-resistant Staphylococcus aureus (MRSA) adalah strain Staphylococcus aureus yang resisten terhadap antibiotik golongan beta laktam. Pasien karier MRSA dinilai meningkatkan kejadian komplikasi paska operasi pada pasien ortopedi. Penelitian ini bertujuan untuk mengetahui gambaran dan prevalensi skrining MRSA pada pasien ortopedi di Bangsal Bedah RS X Riau.  Metode penelitian ini adalah deskriptif dengan rancangan cross-sectional menggunakan data primer dan sekunder responden.  Penelitian ini dilakukan pada 34 responden di Bangsal Bedah RS X Riau sejak Januari 2019 – Maret 2020.  Persentase responden yang memiliki faktor risiko sebagai karier MRSA yaitu: 5,9% dengan riwayat operasi 3 bulan terakhir; 2,9% dengan riwayat penggunaan antibiotik dalam 6 bulan terakhir, 29,4% dengan luka terbuka akut, 11,8% dengan riwayat rawat inap, 0% dengan riwayat kultur MRSA, dan 17,6% merupakan rujukan rumah sakit lain. Pada responden berisiko tersebut ditemukan kolonisasi Staphylococcus aureus pada 9 orang responden (26%) di bagian nasal anterior dan tidak ditemukan adanya bakteri MRSA (0%). Kesimpulan yang didapat dari penelitian ini adalah tidak ditemukannya bakteri MRSA pada seluruh sampel yang diperiksa.

 

Kata Kunci: MRSA, Ortopedi, Skrining, Staphylococcus aureus..

 

ABSTRACT

Methicillin-resistant Staphylococcus aureus (MRSA) is a strain of Staphylococcus aureus that is resistant to beta-lactam antibiotics. Patients with MRSA carrier are considered to increase the incidence of post-operative complications in orthopedic patients. This study aimed to determine the prevalence and illustration of MRSA screening in orthopedic patients in X Hospital Riau. This research method was descriptive with cross-sectional design using primary and secondary data of respondents. This study was conducted on 34 respondents in surgical ward at X Hospital Riau from January 2019 to March 2020. The percentage of respondents who had risk factors as MRSA carriers were: 5.9% with a history of surgery in the last 3 months; 2.9% with a history of antibiotic use in the last 6 months, 29.4% with an acute open wound, 11.8% with a history of hospitalization, 0% with a history of MRSA culture, and 17.6% a referral to another hospital. Colonization of Staphylococcus aureus was found in 9 respondents (26%) in the anterior part of the nose and no MRSA bacteria were found (0%). The conclusion from this study is that MRSA bacteria were not found in all samples because only a few respondents had risk factors for becoming MRSA carrier.

 

Keywords: MRSA, Orthopedic, Screening, Staphylococcus aureus.

References

Akhtar, A., Kadir, H. and Chandran, P., 2014. Surgical site infection risk following pre-operative MRSA detection in elective orthopaedic surgery. J Orthop. Vol. 11(3). Pp= 117-20.

Gonsu, K.H., Kouemo, S.L., Toukam, M., Ndze, V.N. and Koulla, S.S., 2013. Nasal carriage of methicillin resistant Staphylococcus aureus and its antibiotic susceptibility pattern in adult hospitalized patients and medical staff in some hospitals in Cameroon. JMA. Vol. 5(3). Pp= 29-33.

Kelly, J.C., O’Briain, D.E., Walls, R., Lee, S.I., O’Rourke, A. and Mc Cabe, J.P., 2012. The role of pre-operative assessment and ringfencing of services in the control of methicillin resistant Staphlococcus aureus infection in orthopaedic patients. the surgeon, 10(2), pp.75-79.

Kuntaman, K., Hadi, U., Setiawan, F., Koendori, E.B., Rusli, M., Santosaningsih, D., Severin, J. and Verbrugh, H.A., 2016. Prevalence of methicillin resistant Staphylococcus aureus from nose and throat of patients on admission to medical wards of DR Soetomo Hospital, Surabaya, Indonesia. Southeast Asian J. Trop. Med. Public Health .Vol. 47(1). P= 66.

Murphy, E., Spencer, S.J., Young, D., Jones, B. and Blyth, M.J.G., 2011. MRSA colonisation and subsequent risk of infection despite effective eradication in orthopaedic elective surgery. J. Bone Jt. Surg. Vol. 93(4). Pp= 548-51.

Nakamura, M., Shimakawa, T., Nakano, S., Chikawa, T., Yoshioka, S., Kashima, M., Toki, S. and Sairyo, K., 2017. Screening for nasal carriage of Staphylococcus aureus among patients scheduled to undergo orthopedic surgery: Incidence of surgical site infection by nasal carriage. J Orthop Sci . Vol. 22(4). Pp= 778-82.

Nixon, M., Jackson, B., Varghese, P., Jenkins, D. and Taylor, G., 2006. Methicillin-resistant Staphylococcus aureus on orthopaedic wards: incidence, spread, mortality, cost and control. J. Bone Jt. Surg. Vol. 88(6). Pp= 812-7.

Perl, T.M. and Golub, J.E., 1998. New approaches to reduce Staphylococcus aureus nosocomial infection rates: treating S. aureus nasal carriage. Ann Pharmacother. Vol. 32(1). Pp= S7-16.

Rao, N., Cannella, B., Crossett, L.S., Yates, A.J. and McGough, R., 2008. A preoperative decolonization protocol for Staphylococcus aureus prevents orthopaedic infections. Clin. Orthop. Relat. Res. Vol. 466(6). Pp= 1343-48.

Santosaningsih, D., Santoso, S., Budayanti, N.S., Kuntaman, K., Lestari, E.S., Farida, H., Hapsari, R., Hadi, P., Winarto, W., Milheiriço, C. and Maquelin, K., 2014. Epidemiology of Staphylococcus aureus harboring the mecA or Panton-Valentine leukocidin genes in hospitals in Java and Bali, Indonesia. AJTHAB. Vol. 90(4). Pp= 728-34.

Santosaningsih, D., Santoso, S., Verbrugh, H.A. and Severin, J.A., 2017. Risk factors for methicillin-resistant Staphylococcus aureus carriage among patients at admission to the surgical ward in a resource-limited hospital in Indonesia. AJTHAB. Vol. 97(5). Pp= 1310-12.

Shukla, S., Nixon, M., Acharya, M., Korim, M.T. and Pandey, R., 2009. Incidence of MRSA surgical-site infection in MRSA carriers in an orthopaedic trauma unit. J. Bone Jt. Surg. Vol. 91(2). Pp= 225-8.

Siddiqui, A.H. and Koirala, J., 2018. Methicillin resistant Staphylococcus aureus (MRSA). StatPearls Publishing, Treasure Island (FL).

Wong, J.W., Ip, M., Tang, A., Wei, V.W., Wong, S.Y., Riley, S., Read, J.M. and Kwok, K.O., 2018. Prevalence and risk factors of community-associated methicillin-resistant Staphylococcus aureus carriage in Asia-Pacific region from 2000 to 2016: a systematic review and meta-analysis. Clin. Epidemiol. Vol. 10. P=1489

Yano, K., Minoda, Y., Sakawa, A., Kuwano, Y., Kondo, K., Fukushima, W. and Tada, K., 2009. Positive nasal culture of methicillin-resistant Staphylococcus aureus (MRSA) is a risk factor for surgical site infection in orthopedics. Acta Orthop. Vol. 80(4). Pp= 486-90.

Article Metrics

Abstract view(s): 474 time(s)
PDF (Bahasa Indonesia): 660 time(s)

Refbacks

  • There are currently no refbacks.