Formulation And Evaluation Of Telang Flower (Clitoria Ternatea L.) Extract Gel Preparation With Tragacanth As Gelling Agent And Antioxidant Activity Test

Setyo Nurwaini(1*), Alifah Tasya Amanda(2)

(1) Pharmaceutic and Pharmaceutical Technology Laboratory, Faculty of Pharmacy, Universitas Muhammadiyah Surakarta
(2) Pharmaceutic and Pharmaceutical Technology Laboratory, Faculty of Pharmacy, Universitas Muhammadiyah Surakarta
(*) Corresponding Author

Abstract

Telang flower has antioxidant activity as a scavenger of free radicals. Formulation in gel form can facilitate its use as a cosmetic preparation. This study aims to determine the characteristics of telang flower extract gel at different concentrations of tragacanth as a gelling agent and its antioxidant activity.Gel formula of telang flower extract with different concentration levels of tragacanth, namely 3%, 4%, and 5%. Gel evaluation includes organoleptic test, homogeneity, pH, spreadability, stickiness, and viscosity. The best formula will be tested for antioxidant activity.Based on the gel characteristics of telang flower extract, F3 has good physical properties, namely pH value of 7.28 ± 0.06, viscosity of 2133.3 ± 23.09 cP, spreadability of 6.05 ± 0.13 cm, and stickiness of 1.17 ± 0.07 seconds. The telang flower extract exhibited an IC50 value of 71.125 ppm, classifying it as strong antixodant. The IC50 value of telang flower extract gel was 92.867 ppm

Keywords

Gel, telang flower; antioxidant; tragacanth; gelling agent

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References

Andriani D. and Murtisiwi L., 2020, Uji Aktivitas Antioksidan Ekstrak Etanol 70% Bunga Telang (Clitoria ternatea L) dari Daerah Sleman dengan Metode DPPH Antioxidant Activity Test of 70% Ethanol Extract of Telang Flower (Clitoria ternatea L) from Sleman Area with DPPH Method, Jurnal Farmasi Indonesia, 17 (1), 70–76.

Cahyaningsih E., Yuda P.E.S.K. and Santoso P., 2019, Skrining Fitokimia dan Uji Aktivitas Antioksidan Ekstrak Etanol Bunga Telang (Clitoria ternatea L.) Dengan Mmetode Spektrofotometri UV-VIS, Jurnal Ilmiah Medicamento, 5 (1), 51–57.

Farhan M., Putriana R A. and Humaidi F., 2023, Formulasi dan Uji Mutu Fisik Sediaan Gel Ekstrak Bunga Telang (Clitoria ternatea L.) Sebagai Antiseptik Tangan, Jurnal Farmasi dan Herbal, 5 (November), 1–12.

Forestryana D., Fahmi M.S. and Putri A.N., 2020, Pengaruh Jenis dan Konsentrasi Gelling Agent pada Karakteristik Formula Gel Antiseptik Ekstrak Etanol 70% Kulit Buah Pisang Ambon, Lumbung Farmasi: Jurnal Ilmu Kefarmasian, 1 (2), 45–51.

Forestryana D., Hayati A. and Putri A.N., 2022, Formulation and Evaluation of Natural Gel Containing Ethanolic Extract of Pandanus amaryllifolius R. Using Various Gelling Agents, Borneo Journal of Pharmacy, 5 (4), 345–356.

Hafid M., Setiawati H., Pratiwi I., Laspin S. and Audia D., 2019, Formulasi dan Uji Stabilitas Fisik Gel Ekstrak Etil Asetat Daun Sirih Hijau (Piper betle L) Menggunakan Variasi Basis Gel, Journal Pharmacy and Sciences ISSN, 11 (2), 2723–0791.

Nadia S., Sihotang S.H. and Mukharomah S., 2022, Antioxidant Activity Test of Telang Flower (Clitoria ternatea L.) in Serum Preparation with DPPH Method, Journal of Pharmaceutical and Sciences, 5 (2), 394–403.

Nuri R., Suharti S. and Puspariki J., 2021, Formulasi Sediaan Masker Gel Kulit Semangka (Citrullus lanatus) Dengan Menggunakan Tragakan Sebagai Pembentuk Gel (Gelling Agent), Journal of Holistic and Health Sciences, 5 (2), 115–124.

Nurwaini S. and Hafidzatun Nasihah R., 2018, Formulasi Dan Uji Aktivitas Antibakteri Sediaan Hand Gel Ekstrak Daun JambuBiji (Psidium guajava L.), The 7th University Research Colloqium 2018 STIKES PKU Muhammadiyah Surakarta, 24–30.

Nurwaini S. and Saputri I.D., 2018, Pengujian Sifat Fisik dan Aktivitas Antibakteri Sediaan Gel Hand Sanitizer Ekstrak Daun Lidah Mertua (Sansevieria trifasciata Prain), Talenta Conference Series: Tropical Medicine (TM), 1 (3), 078–085.

Nurwaini S. and Sari D.A.P., 2019, Masker Gel Peel-Off Ekstrak Daun Teh Hijau (Camellia Sinensis L.) : Sifat Fisik Dan Aktivitas Antioksidannya, The 9th University Research Colloqium 2019 Universitas Muhammadiyah Purworejo MASKER, 405.

Purwati and Verryanti, 2016, Aktivitas Antioksidan Dan Evaluasi Fisik Sediaan Masker Gel Peel Off Dari Ekstrak Kulit Terung Ungu (Solanum melongena L.), Indonesia Natural Research Pharmaceutical Journal, 1 (2), 10–21.

Putri D.M. and Lubis S.S., 2020, Skrining Fitokimia Ekstrak Etil Asetat Daun Kalayu (Erioglossum rubiginosum (Roxb.) Blum), Amina, 2 (3), 120–121.

Putri W.E. and Anindhita M.A., 2022, Optimization of cardamom fruit ethanol extract gel with combination of HPMC and Sodium Alginate as the gelling agent using Simplex Lattice Design, Jurnal Ilmiah Farmasi, 107–120.

Riswanto F.D.O., Wulandari A.M.F., Ngai F.E., Isabel C.F., Dyatmika A.K.U., Rosari F.P. and Setyaningsih D., 2022, Potensi Daun dan Bunga Telang (Clitoria ternatea L.) sebagai Antioksidan, Medicinus, 35 (2), 43–50.

Samodra G., Alfathani N.F. and Octaviani P., 2023, Uji Aktivitas Antioksidan Ekstrak Etanol Kombinasi Daun Kersen (Muntingia calabura L.) dan Daun Kelor (Moringa oleifera L) Dengan Metode DPPH (2,2-Diphenyl-1-Picrylhydrayl), Pharmacon: Jurnal Farmasi Indonesia, 19–26, 19–26.

Septiani S., Wathoni N. and Mita S.R. mita, 2011, Formulasi Sediaan Masker gel Antioksidan Dari Ekstrak Etanol Biji Belinjo, Fakultas Farmasi Universitas Padjajaran, 2–4.

Shabrina D.R. and Nurwaini S., 2023, Formulation and Physical Evaluation of Sunscreen Spray Gel Preparations From Kersen Leaf Extract (Muntingia calabura L.), Usadha Journal of Pharmacy, 2 (2), 247–256.

Sutrisna E., Trisharyanti I., Munawaroh R. and Dwi Mahendra A., 2015, Efek Antioksidan Ekstrak Etanol 70% Biji Alpukat (Persea americana Mill) Dengan Metode DPPH, University Research Colloquium 2015, (1), 167–170.

Valentina F.E. and Saryanti D., 2023, Formulasi Gel Antibakteri Ekstrak Daun Pandan Wangi (Pandanus amaryllifolius Roxb.) Menggunakan Hydroxy Propyl Methyl Cellulose (HPMC) dan Uji Aktivitas terhadap Staphylococcus aureus Formulation of Antibacterial Gel of Pandan Leaf Extract (Pandanus amary, Pharmacon: Jurnal Farmasi Indonesia, 20 (1), 1–9.

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