Evaluation of the Use of Antibiotics in Chronic Renal Failure Patients in RSUP Dr. Soeradji Tirtonegoro Klaten Period 2014

Gita Ayu Pradina, Zakky Cholisoh

DOI: https://doi.org/10.23917/pharmacon.v14i1.542


Antibiotics are one of the most widely used drugs in curing various kinds of infectious diseases. The use of
antibiotics, especially in chronic renal failure, need to be considered because it can cause nephrotoxicity
in kidneys. The purpose of this study was to evaluate the rational use of antibiotics in RSUP Dr. Soeradji
Tirtonegoro in cases of chronic renal failure in 2014. The evaluation includes the right indication, the
right drug, right patient, and proper dosage. This research is conducted in a manner that is based on a
retrospective medical record belongs to chronic renal failure patients on inpatient RSUP Dr. Tirtonegoro
Klaten 2014. The search results obtained from medical records and evaluation results indicated the use
of appropriate antibiotics as many as 20 cases (55.56%), patients with chronic renal failure who meet the
appropriate criteria are 39 cases (97.7%), use of the right type of antibiotics drugs there were 13 cases
(29,5%), and to use appropriate antibiotics doses were 21 cases (47.7%). Discharge status of patients
with a total of 36 cases (100%) with result of the patient’s health improved. From the result of arithmetic
leukocytes figure, there are 33 cases ( 91.67 % ) with leukocytes count back to normal.

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