Demographic, Clinical, and Antiretroviral Regiment Treatment Characteristics of HIV/AIDS Patients at the Regional General Hospital of Central Papua

Siti Sitatul Mar’ah(1), Burhannudin Ichsan(2), Zakky Cholisoh(3*)

(1) Faculty of Pharmacy, University Muhammadiyah of Surakarta, Indonesia
(2) Faculty of Pharmacy, University Muhammadiyah of Surakarta, Indonesia
(3) Faculty of Pharmacy, University Muhammadiyah of Surakarta, Indonesia
(*) Corresponding Author

Abstract

The incidence of HIV infections in Papua is currently on the rise, primarily due to restricted access to antiretroviral treatment and insufficient support and care. Additionally, there is a lack of awareness among residents in rural or mountainous areas about HIV/AIDS infection, as provided by healthcare professionals. Until now, research data have been scarce on the demographic characteristics, clinical features, and treatment approaches for HIV/AIDS patients in the interior regions of Papua. This data is crucial for devising strategies aimed at enhancing healthcare services for individuals affected by HIV/AIDS.Consequently, this study endeavors to gain insights into the demographic characteristics, clinical features, and treatment modalities for HIV/AIDS patients at the Regional General Hospital of the Central Papua Region. It employs an observational descriptive approach, utilizing medical records of HIV/AIDS patients who visited the Central Papua Regional Government Hospital in June 2023. The findings indicate that, based on demographic data, the majority of patients were, on average, ≤25 years old (60.8%), male (52.5%), married (56.7%), and the highest number of HIV/AIDS cases were among secondary education graduates (40.8%). The majority were employed (67.5%) with incomes below the minimum wage threshold (69.2%). All heterosexual patients exhibited behavioral risk factors, and 4.2% had comorbidities such as hypertension. Tuberculosis was the most common opportunistic infection (17.5%). The highest proportion of individuals with HIV/AIDS were in stage II (66.7%). The predominant antiretroviral treatment regimen was a fixed-dose combination (FDC) containing Tenofovir 300mg, Lamivudine 300mg, and Efavirenz 600mg. The duration of use of ARV therapy in people with HIV / AIDS is at most 1 month.

 

Keywords

Demographic Characteristics, Clinical characteristics, Treatment, HIV/AIDS

Full Text:

PDF

References

Amalia, A., & Rahmawati, F., 2020. Risk Factors of Adverse Drug Reactions of First-line Antiretroviral Therapy in HIV Patients at RSUD Dr. Moewardi. Pharmaciana, 10(2), 201-209. https://doi.org/10.12928/pharmaciana.v10i2.15658

Anggriani, Y., Rianti, A., Pontoan, J., & Juwita, Y., 2019. Analisis Efektivitas Terapi Antiretroviral Pada Pasien HIV/AIDS Rawat Jalan Di RSUP Fatmawati Jakarta Tahun 2016. Jurnal Ilmiah Ibnu Sina, 4(1), 9–18. https://doi.org/10.36387/JIIS.V4I1.212

Anwar, Y., Nugroho, S.A., Tantri N.D., 2018. Characteristics of Sociodemographic, Clinical, And Pattern of Antiretroviral Therapy of HIV/AIDS Patients at RSPI Prof. Dr. Sulianti Saroso in The Period January to June 2016. Pharmaceutical Journal of Indonesia, 15, 1693–3591. https://doi.org.10.30595/pharmacy.v15i1.1216

CDC, 2023. HIV: Centers for Disease Control and Prevention. https://www.cdc.gov/hiv/basics/livingwithhiv/opportunisticinfections.html

Clinical Info HIV, 2021. Offering Information on HIV/AIDS Treatment, Prevention, and Research. https://clinicalinfo.hiv.gov/en

Depkes RI, 2006. Pedoman Pelayanan Kefarmasian untuk ODHA. Departemen Kesehatan republik Indonesia, Jakarta. http://repository.stikim.ac.id/file/22-02-1070.pdf

DinkesProv Papua, 2023. Singkat: Layanan Sistem Informasi Kesehatan Terintergrasi. Dinas Kesehatan Provinsi Papua, Papua. https://dinkes.papua.go.id/

Dirjen PP&PL, 2022. Laporan Perkembangan HIV-AIDS, Penyakit Infeksi Menular Seksual (PIMS) Triwulan 1 Januari-Maret 2022, Direktorat Jenderal Pengendalian Penyakit dan Penyehatan Lingkungan, Jakarta. https://siha.kemkes.go.id/portal/files_upload/Laporan_TW_1_2022.pdf

Faramita, R., & Sumarlan, 2023. Evaluation of Antiretroviral (ARV) Drugs Use in HIV-AIDS Patients Based on The Characteristics at Public Health Center of Wara Palopo City 2019-2022. The Journal of Health Luwu Raya. 9(2), 65–72. https://jurnalstikesluwuraya.ac.id/index.php/eq/article/view/201/159

Hattoh, K. A., Sienso, B. A., & Kuugbee, E. D., 2022. Prevalence of Comorbidities and Associated Factors among HIV Patients Attending Antiretroviral Clinics in the Tamale Metropolis, Ghana. Venereology, 2(1), 1–15. https://doi.org/10.3390/venereology2010001

Kemenkes RI, 2021. Peta Genotyping HIV-1 Papua dan Papua Barat. Balai Litbangkes Papua. Kementerian Kesehatan Republik Indonesia, Jakarta. https://repository.badankebijakan.kemkes.go.id/4302/1/Buku Genotyping HIV_2021.pdf

Kridaningsih, T. N., Widiyanti, M., Adiningsih, S., Hutapea, H. M. L., Fitriana, E., & Natalia, E. I., 2021. Profile of HIV/AIDS Patients Coinfected with Tuberculosis in Bumi Wonorejo Health Centre and Santo Rafael Clinic Nabire, Papua. Jurnal Kedokteran Brawijaya, 31(4), 247–252. https://doi.org/10.21776/ub.jkb.2021.031.04.10

Latif, F., Maria, I.L., & Syafar, M., 2014. Drug Side Effects on Adherence to Antiretroviral Treatment among People Living with HIV/AIDS. Kesmas: National Public Health Journal, 9(2), 101-106. https://doi.org/10.21109/kesmas.v9i2.495

Mulugeta, H., Afenigus, A. D., Haile, D., Amha, H., Kassa, G. M., Wubetu, M., Abebaw, E., & Jara, D., 2021. Incidence and Predictors of Hypertension among HIV Patients Receiving ART at Public Health Facilities, Northwest Ethiopia: A One-Year Multicenter Prospective Follow-Up Study. HIV/AIDS - Research and Palliative Care, 13(10), 889–901. https://doi.org/10.2147/HIV.S329838

Nurhayati, Sudirman, & Afni, N., 2018. Risk Factors of Incident of HIV/AIDS Infection At Anutapura Palu General Hospital. Jurnal Kolaboratif Sains, 1(1), 795–807.

Pessiwarissa, D.N., Sekeon, S.A., & Kalesaran, A.F., 2019. Hubungan Antara Perilaku Beristri Banyak Pada Suku Mee Dengan Kasus HIV/AIDS Di Wilayah Kerja Dinas kesehatan Kabupaten Nabire. Fakultas Kesehatan Masyarakat Universitas Sam Ratulangi, 8(7). https://ejournal.unsrat.ac.id/index.php/kesmas/article/view/27204

Prawira, Y., Uwan, W. B., & Ilmiawan, M. I., 2020. Karakteristik Penderita Infeksi HIV/AIDS di Klinik Voluntary Counseling and Testing Lazarus RS St. Antonius Pontianak Tahun 2017. Jurnal Cerebellum, 5(4A), 1519. https://doi.org/10.26418/jc.v5i4a.43017

Rachmawati, A., Sukarya, S. S., Akbar, A. S., Insan, N., Effendy, S., Tosepu, R., Susanty, S., Tosepu, R., Susanty, S., 2023. Gambaran Karakteristik Pasien HIV/AIDS Di RSUD Kota Kendari Periode 2021-2022. Jurnal Kesehatan Masyarakat Celebes, 4(2). 1-8. https://jkmc.or.id/ojs/index.php/jkmc/article/view/133

Ramadani, P.R., Sumarah, Meilani, N., 2015. Gambaran Tingkat Pengetahuan Tentang Hiv & AIDS pada Siswa Kelas X di SMK Koperasi Yogyakarta Tahun 2015. Kementerian Kesehatan Republik Indonesia Politeknik Kesehatan Yogyakarta Jurusan Kebidanan, 1–12.

Rum, M., & Rakhman, R. (2017). Peran Pemerintah Daerah dalam Pencegahan dan Penanggulangan HIV-AIDS di Kabupaten Merauke. Government: Jurnal Ilmu Pemerintahan, 10(1), 20–29.

Safitri, N. R., Fadraersada, J., & Rusli, R., 2019. Studi Terapi Antiretroviral pada Pasien HIV/AIDS Di Kota Samarinda. Proceeding of Mulawarman Pharmaceuticals Conferences, 9, 7–13. https://doi.org/10.25026/mpc.v9i1.342

Saki, M., Kermanshahi, S. M. K., Mohammadi, E., & Mohraz, M., 2015. Perception of Patients with HIV/AIDS from Stigma and Discrimination. Iranian Red Crescent Medical Journal, 17(6), 1-7. https://doi.org/10.5812/ircmj.23638v2

Syafirah, Y., Rahmatini, Bahar, E., 2020. Gambaran Pemberian Regimen Antiretroviral pada Pasien HIV/AIDS di RSUP Dr. M. Djamil Padang Tahun 2017. Jurnal Kesehatan Andalas, 9(15), 147-155. http://jurnal.fk.unand.ac.id

Tatiparthi, R., & Mamo, Y., 2015. Prevalence of ADRs and Associated Factors of Antiretroviral Treatment on HIV Positive Adults at Jush. Indian Journal of Pharmacy Practice, 7(4), 8–15. https://doi.org/10.5530/ijopp.7.4.3

WHO, 2020. HIV/AIDS. World Health Organization. https://www.who.int/news-room/fact-sheets/detail/hiv-aids?gclid=CjwKCAjw69moBhBgEiwAUFCx2CIHzxFIezMkpFlCehrJx_k3oprT5FgNu-4c8ee-ewmgWbDlW2klEhoCpoQQAvD_BwE

Yuliandra, Y., Nosa, U. S., Raveinal, R., & Almasdy, D., 2017. Antiretroviral therapy on HIV/AIDS Patients in Dr. M. Djamil Hospital Padang: Socio-demographic Analysis and Drug Evaluation. Jurnal Sains Farmasi & Klinis, 4(1), 1-8. https://doi.org/10.29208/jsfk.2017.4.1.173

Yuniarti, N., Yuswar, M. A., & Untari, E. K., 2020. Kejadian interaksi obat pada pasien HIV/AIDS yang menerima antiretroviral di RSUD Dr. Soedarso Pontianak periode 2018. Jurnal Cerebellum, 6(1), 6-11. https://doi.org/10.26418/jc.v6i1.43345

Yunior, N., & Wardani, I. K. F., 2018. Faktor –Faktor Yang Berhubungan Dengan Kejadian HIV/AIDS Di Rsud Kabupaten Bekasi Tahun 2018. Jurnal HIV/AIDS, 1–8.

Article Metrics

Abstract view(s): 263 time(s)
PDF: 269 time(s)

Refbacks

  • There are currently no refbacks.